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Home - Products - Cell Cycle/DNA Damage - Integrin - Valategrast hydrochloride

Valategrast hydrochloride

CAS No. 828271-96-1

Valategrast hydrochloride( R-411 | RO-0272441 | RO-27-2441 | R411 | RO 0272441 | RO 27 2441 )

Catalog No. M16076 CAS No. 828271-96-1

Valategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Valategrast hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Valategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
  • Description
    Valategrast hydrochloride is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.Asthma Discontinued.
  • In Vitro
    Valategrast (hydrochloride) contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
  • In Vivo
    ——
  • Synonyms
    R-411 | RO-0272441 | RO-27-2441 | R411 | RO 0272441 | RO 27 2441
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    Integrin
  • Research Area
    Inflammation/Immunology
  • Indication
    Asthma

Chemical Information

  • CAS Number
    828271-96-1
  • Formula Weight
    641.411
  • Molecular Formula
    C30H33Cl4N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OCCN(CC)CC)[C@H](CC1=CC=C(NC(C2=C(Cl)C=CC=C2Cl)=O)C=C1)NC(C3=C(C)C=CC=C3Cl)=O.[H]Cl
  • Chemical Name
    2-(diethylamino)ethyl (2S)-2-[(2-chloro-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoate hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sidduri A, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82.
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